Englisch > Deutsch Naturwissenschaften Biologie, Biochemie, Mikrobiologie

What is often missing from CRISPR debates is an understanding of technical limitations that could impact how and when CRISPR is used in human gene-editing applications, writes David Edgell, professor of biochemistry at Western University, Canada. One of the biggest issues when trying to modify human DNA is the problem of off-target effects. While Edgell's article is about medical applications in humans of the CRISPR gene-editing tool, the same problem of off-target effects (as well as unintended effects at the ***on-target editing site***) occurs in the gene editing of food crops and animals.

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